With prospective title contenders flexing their muscles and the relegation battle already taking shape, this promises to be the most compelling weekend of the Premier League season so far.
With such a lot at stake at both ends of the table, Press Association Sport picks out five of the most pertinent pointers that this Saturday’s action is likely to bring.
And the Frenchman’s reaction – having received a sort-of vote of confidence from his manager – could go a long way towards shaping United’s season. A fine performance and a good win, and the training ground spat from Wednesday could be as good as forgotten. But another defeat for United could make Mourinho’s reign seem increasingly untenable.
Hazard a guess